The safety and efficacy of inhalation of H2 gas during PCI in patients with acute myocardial infarction

The safety and efficacy of inhalation of H2 gas during PCI in patients with acute myocardial infarction - Inhalation of H2 gas in patients with acute myocardial infarction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006825

Enrollment

Registered

2011-12-04

Start date

2012-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

H2 gas inhalation group: H2-mixed gas (H2 1.3%, O2 26%, N2 74%) Patients who suspect that they are having an acute myocardial infarction at an emergency room start to inhale gas and continue to inhal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ST-segment elevation myocardial infarction Within 24 hours following the onset of chest pain

Exclusion criteria

Exclusion criteria: Shock (BP<90mmHg) Severe hypoxia (SpO2<90%) Sustained VT or VF Post-cardiopulmonary resuscitation Patients with absolute contraindications to MRI scans

Design outcomes

Primary

Measure	Time frame
Evaluation of the extent of myocardial lethal ischemia-reperfusion injury by cardiovascular magnetic resonance imaging 7 days after acute myocardial infarction	—

Secondary

Measure	Time frame
Angiographic assessment of reperfusion by TIMI flow grade and myocardial blush grade Assessment of reperfusion by ST resolution Assessment of infarct size by area under the curve-creatine phosphokinase (CPK) Assessment of left ventricular failure by Killip classification Evaluation of wall motion abnormalities and left ventricular ejection fraction by cine MRI 7 days after acute myocardial infarction Evaluation of left ventricular ejection fraction and infarct size by cardiac MRI imaging	—

Measure

Time frame

Angiographic assessment of reperfusion by TIMI flow grade and myocardial blush grade Assessment of reperfusion by ST resolution Assessment of infarct size by area under the curve-creatine phosphokinase (CPK) Assessment of left ventricular failure by Killip classification Evaluation of wall motion abnormalities and left ventricular ejection fraction by cine MRI 7 days after acute myocardial infarction Evaluation of left ventricular ejection fraction and infarct size by cardiac MRI imaging

—

Countries

Japan

Contacts

Public ContactMotoaki Sano

Keio University School of Medicine Department of Cardiology

msano@a8.keio.jp03-5363-3874

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026