A randomized controlled trial of lanthanum carbonate versus calcium carbonate on coronary artery calcification in patients new to dialysis

A randomized controlled trial of lanthanum carbonate versus calcium carbonate on coronary artery calcification in patients new to dialysis - Effect of lanthanum carbonate on coronary artery calcification in patients new to dialysis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006808

Enrollment

100

Registered

2011-12-01

Start date

2011-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal disease (at the induction of dialysis)

Interventions

lanthanum carbonate calcium carbonate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients new to hemodialysis with hyperphosphatemia

Exclusion criteria

Exclusion criteria: 1)Patients who have contraindication to lanthanum carbonate or calcium carbonate 2)Patients with history of parathyroidectomy 3)Gastrointestinal disorder 4)Patients with history of illeus 5)CAPD(continuous ambulatory peritoneal dialysis) 6)Pregnant and breast-feeding 7)Patients judged as being inappropriate for this study by investigators

Design outcomes

Primary

Measure	Time frame
Changes of coronary artery calcification score (Agatston score)	—

Secondary

Measure	Time frame
echocardiography, heart valve calcification, aortic calcification, vascular stiffness, carotid IMT, bone density, bone metabolic markers, ADMA, oxidative stress, high-sensitive CRP	—

Countries

Japan

Contacts

Public ContactHideki Fujii

Kobe university graduate school of medicine Division of nephrology and kidney center

fhideki@med.kobe-u.ac.jp(078)382-6500

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026