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'Smoldering' autoimmune inflammatory pathophysiology in epilepsies

'Smoldering' autoimmune inflammatory pathophysiology in epilepsies - Autoimmune inflammatory pathophysiology in epilepsies

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000006800
Enrollment
50
Registered
2012-01-04
Start date
2012-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Interventions

None listed

Sponsors

Kyoto University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Non-infectious, so-called smoldering encephalitis cases with medically intractable epilepsy during their chronic course. 2) Patients with partial epilepsy with chronic and elderly onset of epilepsy at times seem cryptogenic. 3) Relapsing cases after surgical resection of epileptic foci. 4) Epileptic patients with amygdalar enlargement with MRI, but without increased glucose metabolism by FDG-PET.

Exclusion criteria

Exclusion criteria: Patients with dementia

Design outcomes

Primary

MeasureTime frame
Clinical course including auto-antibody titer and other laboratory results, imaging findings and results of neuropsychological tests

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026