Type 2 diabetes mellitus
Conditions
Interventions
sitagliptin 50mg for 4 months From 2nd day of a medication start, all patients are equiped with a CGM for four days. SMBG is also done 6 times per day. If FPG is more than 130mg/dl or PPG is more th
Sponsors
Yokohama City University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)before test registration - the meal and exercise cure for one month or more or a meal and an exercise cure, and diabetic medicine (aTZD,BG,SU, alpha-GI) and inpatient 2)HbA1c (JDS):more than 6.6%, less than 16.6% 3)Type 2 diabetes 4)Pts with written IC 5)Age more than 20, less than 85
Exclusion criteria
Exclusion criteria: 1)severe ketosis, diabetic coma within 6 months 2)severe infection, before operation, severe trauma 3)severe hepatic dysfunction 4)or severe renal dysfunction (eGFR: more than 1.5mg/dl) 5)Patients who use of insulin 6)pregnacy 7)Allergy for sitagliptin, nateglinide,liraglutide and exenatide 8)Patients judged by the investigator to be ineligible for some other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Standard deviation of blood glucose by CGM | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)averate blood glucose, MAGE by CGM 2)FPG and PPG at 1, 2, 3, 4, 5, 6, 7 days of treatment 3)%chagne of FPG, HbA1c,IRI,CPR, a from baseline | — |
Countries
Japan
Contacts
Public ContactErina Shigematu
Yokohama City University Medical Center Department of Endocrinology and Diabetes
Outcome results
None listed