Guideline-based antibiotics therapy versus empirical therapy for nursing and healthcare-associated pneumonia: A randomized controlled trial

Guideline-based antibiotics therapy versus empirical therapy for nursing and healthcare-associated pneumonia: A randomized controlled trial - Antibiotics choice in NHCAP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006792

Enrollment

100

Registered

2011-12-01

Start date

2011-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nursing and healthcare-associated pneumonia

Interventions

Guideline-based antibiotics choice empirical choice (antibiotics use recommended in treatment category B)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed as NHCAP, and classified into treatment category B or C.

Exclusion criteria

Exclusion criteria: (1) Known severe allergy to any drugs. (2) Patients receiving broad-spectrum antibiotics before admission. (3) Fatal and severe underlying disease, malignancy, COPD, heart failure and so on. (4) Patients who cannot safely receive cessation of eating or hydration as a treatment for pneumonia because of dementia.

Design outcomes

Primary

Measure	Time frame
In-hospital mortality and relapses of pneumonia occurring within 30 days following admission.	—

Secondary

Measure	Time frame
Initial choice of antibiotics, the number of drug-change and duration of therapy. Adverse effects from antibiotics therapy. Cost of medical care for pneumonia.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026