scabies
Conditions
Interventions
First, 200 ug/kg ivermectin are administerd on fast. A week later, same doses of ivermectin are administerd on food .Observation is continued one week after second administration..
Sponsors
Laboratory of medical safety management, Tokyo University of Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients who were diagnosed with scabies. 2)Patients who needed hospitalization by scabies or other disease. 3)Subjects who understood the requirements of the study and signed the informed consent forms.
Exclusion criteria
Exclusion criteria: 1)Subjects who had in the past or currently have following diseases. ;hepatic diseases ;other diseases which doctor in attendance considered to influence in results of study, or be penalized by administration of ivermectin. 2)Subjects who consumed excessive amounts of coffee or beverage containing caffeine.(over eight cups a day) 3)Drug or alcohol abuser. 4)Illegal drug constant user. 5)Men and women who donated two hundred milliliter of blood within four weeks prior to commencement of this study, or men who donated four hundred milliliter of blood within twelve weeks prior to commencement of this study, and women who donated four hundred milliliter of blood within sixteen weeks prior to commencement of this study. 6)Subjects who participated in another clinical trials with an investigational agent within four weeks prior to commencement of this study. 7)Subjects who had history of hypersensitivity to constituent of STROMECTOL 8)Subjects who are judged as inadequate by doctor in attendance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To analyze ivermectin in blood after fed and fasted administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| To analyze ivermectin in skin, mites after fed and fasted administration. | — |
Countries
Japan
Contacts
Public ContactMasayo Komoda
Tokyo University of Science Faculty of Pharmaceutical Sciences
Outcome results
None listed