Can therapeutic intervention to the decrease of cerebral regional oxygen saturation during abdominal surgery prevent the occurrence of postoperative cognitive dysfunction in elderly patients?

Can therapeutic intervention to the decrease of cerebral regional oxygen saturation during abdominal surgery prevent the occurrence of postoperative cognitive dysfunction in elderly patients? - Does therapeutic intervention to cerebral hypoxia improve the postoperative cognitive dysfunction?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006788

Enrollment

250

Registered

2011-12-01

Start date

2011-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases requiring abdominal surgery

Interventions

Increase of inspiratory oxygen concentration none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologists Classification I - III scheduled for undergoing elective abdominal surgery requiring more than 2 hours.

Exclusion criteria

Exclusion criteria: Patients with a history of cerebral ischemia, cerebral infarction or score of mini mental state examination less than 23, hospital stay within 3 days.

Design outcomes

Primary

Measure	Time frame
Results of mini mental state examination (MMSE) test	—

Secondary

Measure	Time frame
Bispectral index	—

Countries

Japan

Contacts

Public ContactRyu Okutani

Osaka City General Hospital and Children's Hospital Department of Anesthesiology

ryuokutani0909@ybb.ne.jp81-6-6929-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026