Psychophysiological evaluation of effect of ingestion of oil extracted from krill on brain function

Psychophysiological evaluation of effect of ingestion of oil extracted from krill on brain function - Psychophysiological evaluation of effect of krill oil on brain function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006775

Enrollment

Registered

2011-12-20

Start date

2010-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

sample: krill oil dose: 2g/day period: 12weeks sample: sardine oil dose: 2g/day period: 12weeks sample: middle-chain triglycerides (placebo) dose: 2g/day period: 12weeks

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy and right-handed

Exclusion criteria

Exclusion criteria: 1) administration of regular medication 2) history of mental disorder or cerebrovascular disease 3) serious liver, kidney, heart, respiratory, endocrine, or metabolic diseases 4) marked abnormal findings for results of blood and urine tests 5) food allergies to fish or crustaceans

Design outcomes

Primary

Measure	Time frame
Before starting ingestion, at week 6 and 12, 1) the changes in the oxy-Hb concentration during calculation tasks, and results of performance 2) the changes in oxy-Hb concentration and ERP during memory tasks, and results of performance 3) psychological tests by using POMS, STAI, and the visual analog scale (VAS)	—

Secondary

Measure	Time frame
Before starting ingestion, at week 6 and 12, 1) height, weight, and blood pressure 2) results of blood test (white blood cell count, red blood cell count, hemoglobin, and hematocrit) 3) results of blood biochemical test (GOT, GPT, gamma-GTP, creatinine, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, blood sugar, HbA1c, and uric acid) 4) fatty acids in plasma (dihomo-gamma linorenic acid, arachidonic acid, EPA, and DHA) 5) results of urine test (occult blood, urinary protein, urinary sugar, and urobilinogen) 6) nutrient intake by food frequency method	—

Measure

Time frame

Before starting ingestion, at week 6 and 12, 1) height, weight, and blood pressure 2) results of blood test (white blood cell count, red blood cell count, hemoglobin, and hematocrit) 3) results of blood biochemical test (GOT, GPT, gamma-GTP, creatinine, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, blood sugar, HbA1c, and uric acid) 4) fatty acids in plasma (dihomo-gamma linorenic acid, arachidonic acid, EPA, and DHA) 5) results of urine test (occult blood, urinary protein, urinary sugar, and urobilinogen) 6) nutrient intake by food frequency method

—

Countries

Japan

Contacts

Public ContactYoshihiko Koga

Kyorin University School of Medicine Department of Neuropsychiatry

koga@ks.kyorin-u.ac.jp0422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026