Randomized controlled trial to examine efficacy of late evening snack for the patients undergoing local treatment of hepatocellular carcinoma.

Randomized controlled trial to examine efficacy of late evening snack for the patients undergoing local treatment of hepatocellular carcinoma. - Randomized controlled trial to examine efficacy of late evening snack for the patients undergoing local treatment of hepatocellular carcinoma.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006753

Enrollment

100

Registered

2011-11-21

Start date

2011-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

LES group: dietary advice and one package of Aminoleban EN as LES before sleep. control group: dietary advice only.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who will be receiving radiofrequency ablation for hepatocellular carcinoma.

Exclusion criteria

Exclusion criteria: 1)extrahepatic metastasis 2)portal vein tumor invasion 3)rupture of hepatocellular carcinoma 4)more than 3mg/L of total bilirubin level 5)uncontrollable ascites 6)more than 2mg/L of serum creatinine level 7)history of hepatic coma within a month 8)reconstruction of the biliary tract such as pancreatoduodenectomy 9)allergy for milk (contraindication of Aminoleban EN)

Design outcomes

Primary

Measure	Time frame
Change of nutrition condition using Masstrichit Index(MI) and COUNT	—

Secondary

Measure	Time frame
Onset rate of life-threatening event (liver failure, esophagogastric varix rupture, tumor rupture, recurrence of hepatocellular carcinoma and death.(death due to any reason). Change of subjective symptoms.	—

Countries

Japan

Contacts

Public ContactShinpei Sato

Kyoundo Hospital gastroenterology and hepatology

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026