The suppressant action of the surgical stress

The suppressant action of the surgical stress - The suppressant action of the surgical stress

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006718

Enrollment

100

Registered

2011-11-14

Start date

2011-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer, Gasatric cancer, Colorectal cancer, Hepatocellular carcinoma, Colangiocellular carcinoma, Bile duct cancer, pancreatic carcinoma

Interventions

To administere eicosapentaenoic acid before surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Cancer patients (2) Written informed conscent to recieve this chemotherapy (3) More than 20 years old (4) Eastern Cooperative Oncology Groupe (ECOG) performance status of 0-2 (5) Life expectancy mor than 12 weeks (6) The patients can take food oraly

Exclusion criteria

Exclusion criteria: (1) Infection or inflammatory case (2) Severe heart disease (3) Severe complicated case such as ileus, interstitial pneumonia, uncontrolled DM, liver cirrhosis etc (4) others

Design outcomes

Primary

Measure	Time frame
To evaluate the ability of EPA to suppress oxidative stress when administered before surgery.	—

Secondary

Measure	Time frame
To evaluate the oxidant/antioxidant balance before, during and after surgery.	—

Countries

Japan

Contacts

Public ContactHisako Kubota

Kawasaki Medical school Digestive Surgery

kubota@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026