Open-label trial of long-term D-cycloserine for schizophrenia

Open-label trial of long-term D-cycloserine for schizophrenia - Long-term D-cycloserine trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006654

Enrollment

Registered

2011-11-02

Start date

2011-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

D-cycloserine group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with schizophrenia diagnosed by DSM-IV criteria

Exclusion criteria

Exclusion criteria: D-cycloserine contraindication Ongoing cognitive behavioral therapy Drug abuse Possible pregnancy History of electroconvulsive therapy in 12 weeks Suicide attempt within 24 weeks Epilepsy Severe brain disease Severe somatic disease

Design outcomes

Primary

Measure	Time frame
PANSS SANS	—

Secondary

Measure	Time frame
BACS CDSS GAF DIEPSS AIMS EQS Exploratory Eye Movement	—

Countries

Japan

Contacts

Public ContactAkihito Uezato

Tokyo Medical and Dental University Graduate School Department of Psychiatry and Behavioral Sciences

uezato-tmd@umin.ac.jp03-5803-5242

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026