Investigation of efficacy and safety for periodontal regeneration using controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel

Investigation of efficacy and safety for periodontal regeneration using controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel - Periodontal regeneration with controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006594

Enrollment

Registered

2011-10-23

Start date

2012-07-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

Controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel is transplanted to periodontal bone defect during the flap procedure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients having intrabony periodontal defects with probing pocket depth more than 4 mm after initial preparation. Radiographic evidence of intrabony defects had to exist 2) Patients who can give informed consent themselves in writing

Exclusion criteria

Exclusion criteria: 1) Patients with any systemic illness known to affect the outcomes of periodontal regeneration 2) Pregnancy and/or lactation 3) The habit of smoking or use of other tobacco prodacts 4) Other(doctors dicision)

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study is to evaluate the efficacy for periodontal regeneration using controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydroge	—

Secondary

Measure	Time frame
The secondary outcome of this study is to evaluate the clinical safety for periodontal regeneration using controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel	—

Countries

Japan

Contacts

Public ContactMikimoto Kanazashi

Tsurumi University School of Dental Medicine Department of Periodontology

kanazashi-m@tsurumi-u.ac.jp045-581-1001

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026