Colorectal cancer patients performed laparoscopic surgery at high risk of VTE
Conditions
Interventions
None listed
Sponsors
Kansai Medical University Hirakata hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Colorectal cancer patients performed laparoscopic surgery with VTE risk factor listed Japanese VTE prevention guideline 2. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patient who meet contraindication or precaution in package insert of anticoagulants such as Fondaparinux, UFH, LMWH, and Danaparoid 2. Patient who have experience of lower limb orthopedic surgery, abdominal surgery, cardiovascular surgery within 3 month of enrollment 3. Patient who receive contra indicated concomitant drug within 1 week after Fondaparinux administration. 4. VTE patient diagnosed before surgery 5. Patient whose D-dimer above 1 micro gram before surgery 6. Patient who have history of arterial thromboembolism 7. Drug addiction or alcohol abuse. 8. Patient who scheduled other surgery during the study 9. Pregnant women or women who have possibility of pregnancy. 10. Patient who judged inadequate to join the study by the doctor in charge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of symptomatic/ asymptomatic DVT and symptomatic PTE | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of major bleeding | — |
Countries
Japan
Contacts
Public ContactKatsuji Tokuhara
Kansai Medical University Hirakata hospital Department of Surgery
Outcome results
None listed