Japanese cedar pollinosis
Conditions
Interventions
Subject takes levocetirizine hydrochloride 5mg and fluticasone furoate nasal spray 110 micro g. once a day at previous night of pollen exposure.
Subject takes levocetirizine hydrochloride 5mg and flut
Sponsors
Nippon Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) CAP-RAST score against Japanese cedar pollen over class 2 within the last 2 years. 2) Patients who have typical seasonal allergic rhinitis symptoms for at least 2 years. The presence of moderate and more symptoms, subject with main symptom of nasal congestion. 3) Written informed consent is required.
Exclusion criteria
Exclusion criteria: 1) A hisotry of nasal and/or ocular disease 2) Evidence of upper and/or lower respiratory tract inflammation within 2 weeks prior to IC 3) An episode of sinusitis within 30 days prior to IC 4) A hisotry of treatment with steroid injection within 6 months prior to IC 5) A hisotry of treatment with steroid (oral and topical) within 4 weeks prior to IC 6) A history of asthma (include of child asthma) 7) A history of anaphylaxis 8) Patients who have the hypersensitivity to study drugs 9) Patients with desensitization therapy 10) Patients with nasal anatomical deformities leading to obstruction within 1 year prior to IC 11) Patients with cardiac, renal disease, or hepatic insufficiency 12) Pregnancy, breast-feeding woman, potencial pregnancy, patient who wish to become pregnant during this study 13) Patients who were judged to be unsuitable for patient enrollment by the doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative incidence rate of nasal symptoms after 3hr-pollen exposure | — |
Secondary
| Measure | Time frame |
|---|---|
| Nasal symptoms Ocular symptoms Oral-pharyngeal symptoms Amount of nasal discharge Number of sneezing | — |
Countries
Japan
Contacts
Public ContactKiyochika Suematsu
Medical Corporation Shinanokai, Samoncho Clinic Pharmaceutical Dept.,
Outcome results
None listed