A study of appropriate fluid volume for resuscitation (evaluation of stroke volume variation under spontaneous respiration)

A study of appropriate fluid volume for resuscitation (evaluation of stroke volume variation under spontaneous respiration) - A study of appropriate fluid volume for resuscitation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006484

Enrollment

100

Registered

2011-10-05

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with a decrease in effective intravascular volume

Interventions

Measuring invasive arterial blood pressure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) &#8805; 16 year-old 2) Patients with a decrease in effective intravascular volume and fluid resuscitation therapy ( hemorrhagic shock, dehydration, septic shock, and so on) 3) Patients with measuring invasive arterial blood pressure

Exclusion criteria

Exclusion criteria: 1) Patients rejected intensive care management 2) Patients with terminal stage of malignant disease 3) Patients without informed consent

Design outcomes

Primary

Measure	Time frame
No increasing of SVI under fluid resuscitation shows that the effective intravascular volume is achieved by fluid resuscitation. At this point, the following parameters are measured, vital signs, diameter of IVC, blood gas data, arterial lactate, ejection fraction, central venous pressure, ScvO2, and SVV value. We detect the best parameter for appropriate fluid resuscitation volume using receiving operating curve analysis.	—

Measure

Time frame

No increasing of SVI under fluid resuscitation shows that the effective intravascular volume is achieved by fluid resuscitation. At this point, the following parameters are measured, vital signs, diameter of IVC, blood gas data, arterial lactate, ejection fraction, central venous pressure, ScvO2, and SVV value. We detect the best parameter for appropriate fluid resuscitation volume using receiving operating curve analysis.

—

Countries

Japan

Contacts

Public ContactAkiyoshi Hagiwara

National center for global health and medicine Emergency medicine and critical care

ahagiwar@hosp.ncgm.go.jp03-3202-7181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026