Double blind randomized controlled trial to assess mediastinal emphysema after esophageal endoscopic submucosal dissection with insufflation of carbon dioxide

Double blind randomized controlled trial to assess mediastinal emphysema after esophageal endoscopic submucosal dissection with insufflation of carbon dioxide - Double blind randomized controlled trial to assess mediastinal emphysema after esophageal endoscopic submucosal dissection with insufflation of carbon dioxide

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006441

Enrollment

Registered

2012-03-31

Start date

2011-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal cancer

Interventions

insufflation of CO2 or Air Multi-detector row computed tomography (MDCT) was carried out immediately after ESD. A conventional chest X-ray was taken the next day.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients who undergo esophageal ESD

Exclusion criteria

Exclusion criteria: inability to provide informed consent, severe chronic obstructive pulmonary disease, and synchronous multiple lesions.

Design outcomes

Primary

Measure	Time frame
incidence and severity of post-ESD ME in patients receiving CO2 insufflation	—

Secondary

Measure	Time frame
clinical course, treatment results, safety	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026