Analysis of intestinal flora by T-RFLP in patients with ulcerative colitis in remission phase and Investigation on the remission-maintaining by probiotic preparation

Analysis of intestinal flora by T-RFLP in patients with ulcerative colitis in remission phase and Investigation on the remission-maintaining by probiotic preparation - Analysis of intestinal flora by T-RFLP in patients with ulcerative colitis in remission phase and Investigation on the remission-maintaining by probiotic preparation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006424

Enrollment

150

Registered

2011-09-28

Start date

2010-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with ulcerative colitis in remission phase

Interventions

Bio-Three administration group: 3 tablets t.i.d for 12 months Pracebo administration group: 3 tablets t.i.d for 12 months Non-administration group: ordinary treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with ulcerative colitis in remission phase when have over 4 weeks.

Exclusion criteria

Exclusion criteria: 1)Patients with serious cardiovascular disease. 2)Patients with serious kidney disease. 3)Patients with hypotension (systolic blood pressure below 80mmHg). 4)Patients with a history of shock caused during extracorporeal circulation treatment. 5)Patients who have complicated severe infectious with sepsis or pneumonia. 6)Patients with hemoglobin(Hb) less than 10mg/dl. 7)Patients who have been in treatment with Leukocytapheresis(LCAP) , Granulocytapheresis(GCAP) or Immunosuppressive drug treatment.

Design outcomes

Primary

Measure	Time frame
Non-relapse rate	—

Secondary

Measure	Time frame
Analysis of intestinal flora and organic acid	—

Countries

Japan

Contacts

Public ContactRyuichi Furukawa

Toho University Sakura Medical Center Department of Internal Medicine

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026