Comparative effects of amiodarone vs bisoprolol for postoperative atrial fibrillation

Comparative effects of amiodarone vs bisoprolol for postoperative atrial fibrillation - Comparative effects of amiodarone vs bisoprolol for postoperative atrial fibrillation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006348

Enrollment

Registered

2011-09-20

Start date

2015-10-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

valve disease or coronary artery disease with hypertension

Interventions

Take amiodaron 400 mg a day for 7 days preoperatively and resume taking amiodaron 200 mg a day on the first postoperative day Take bisoprolol 5 mg a day for 7 days preoperatively and resume taking bis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: those who has hypertension and going to have cardiac operation such as valve replacement, valve plasty or coronary artery bypass grafting

Exclusion criteria

Exclusion criteria: low cardiac output, congested heart failure, emergency operation, paroxysmal atrial fibrillation or flutter, PSVT, pacemaker or ICD implant, those who takes group 1 or 3 antiarrhythmic medication, hepatic insufficiency, bradycardia less than HR 50/min, more than second degree atrioventricular block, hemodyalysis patients, those who has beta blocker preoperatively

Design outcomes

Primary

Measure	Time frame
new onset of postoperative atrial fibrillation	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026