Non-squamous non-small cell lung cancer
Conditions
Interventions
DTX+BEV
Sponsors
University hospital, Hirosaki University School of Medicine Cardiology,respiratory medicine and nephrology
Hirosaki Central Hospital Natonal Hospital Orgnization Hirosaki Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or cytrologically confirmed diagnosis of NSCLC (Non squamous cell carcinima) 2)No prior systemic treatment advanced NSCLC 3)Tumors must have measurable disease 4)ECOG performance status 0 or 1 5)Patients aged 70- years 6)Written informed consent from the patients 7)No problem adequate organ function
Exclusion criteria
Exclusion criteria: 1)Subjects with interstitial pneumonia or pulmonary fibrosis. 2)Uncontrolled systematic disease 3)Uncontrolled active infection 4)No other active malignancies 5)Concurrent use of steroid therapy 6)Subjects with brain metastases 7)Uncontrolled pleural effusion and ascites 8)have had or require continuous oral administration of hemostat/have had or require injectable administration of hemostat 9)Pregnant patients 10)Have a bleeding diathesis 11)Tumor invasion to major vessels 12)Cavity in tumor 13)History of uncontrolled gastroduodenal ulcer 14)Uncontrolled hypertension 15)Symptomatic heart failure,unstable angina, uncontrolled arrhythmia, myocardial infarction within 1 year 16)Symptomatic cerebrovasucular disease 17)Any other reason that,in the opinion of the investugator precludes the subject from participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RR: response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| PFS: progression free survival OS: overall survival safety | — |
Countries
Japan
Contacts
Public ContactHisashi Tanaka
University hospital, Hirosaki University School of Medicine Cardiology,respiratory medicine and nephrology
Outcome results
None listed