A randomized controlled trial for the prevention of Japanese cedar pollinosis by Levocetirizine in the pollen exposure chamber

A randomized controlled trial for the prevention of Japanese cedar pollinosis by Levocetirizine in the pollen exposure chamber - A randomized controlled trial for the prevention of Japanese cedar pollinosis by Levocetirizine in the pollen exposure chamber

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006318

Enrollment

Registered

2011-09-09

Start date

2011-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cedar pollinosis

Interventions

The first day of pollen exposition (1hr) is defined Day0. The second day of pollen exposition (3hr) is defined Day1. 7days berore pollen exposition are defined as Day-7 - Day-1. Group A takes Levoceti

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who have medical history of cedar pollinosis for more than 2 years. 2)Positive specific IgE to cry j1/2 antigen(CAP-RAST>=class2) 3)Patients who develop clear symptoms by a pollen exposure for 3 hours.

Exclusion criteria

Exclusion criteria: 1)Pregnant women and those at risk of pregnancy 2)lactating woman 3)Complication of the other nasal-paranasal disease 4)Use of other antiallergic agent 5)Allergia for an ingredient of Levocetirizine 6)severe renal disturbance (creatinine clearance: less than 10mL/min)

Design outcomes

Primary

Measure	Time frame
Total nasal symptom score in Day1 (3hr of pollen exposition).	—

Secondary

Measure	Time frame
1.A symptom in a chamber in Day1. 2.A symprom after pollen exposition in Day1. 3.Nasal nitric oxide before and after pollen exposition. 4.Safty.	—

Countries

Japan

Contacts

Public ContactSyuji Yonekura

Chiba University Graduate School Department of Otorhinolaryngology

043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026