Comparison of clinical outcomes of various treatment regimens as induction and maintenance therapy for lupus nephritis

Comparison of clinical outcomes of various treatment regimens as induction and maintenance therapy for lupus nephritis - Comparison of clinical outcomes of various treatment regimens as induction and maintenance therapy for lupus nephritis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006309

Enrollment

Registered

2011-10-01

Start date

2011-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lupus nephritis

Interventions

moderate dose of intravenous cyclophosphamide (500-700mg/body/month) as induction therapy, tacrolimus(1-3mg/day) as maintenance therapy moderate dose of intravenous cyclophosphamide (500-700mg/body/mo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patient of active lupus nephritis

Exclusion criteria

Exclusion criteria: patient who has contraindication of drugs including cyclophosphamide, azathioprine and tacrolimus. patient who has contraindication of apheresis therapy

Design outcomes

Primary

Measure	Time frame
renal remission rate	—

Secondary

Measure	Time frame
relapse rate duration to remission duration to relapse	—

Countries

Japan

Contacts

Public ContactKen Yamaji

Juntendo University School of Medicine Department of Internal Medicine and Rheumatology

k.yamaji@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026