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Survey to evaluate the effect of antiemetic therapy on dose intensity of EC/FEC or AC regimen as well as prognosis in patients with breast cancer (KBCSG1112)

Survey to evaluate the effect of antiemetic therapy on dose intensity of EC/FEC or AC regimen as well as prognosis in patients with breast cancer (KBCSG1112) - Survey to evaluate the effect of antiemetic therapy on dose intensity of EC/FEC or AC regimen as well as prognosis in patients with breast cancer (KBCSG1112)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000006284
Enrollment
500
Registered
2011-09-09
Start date
2011-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

None listed

Sponsors

KBCSG (Kinki Breast Cancer Study Group)
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Breast cancer patient (a) planned to have three cycles or more of EC/FEC or AC regimen as pre/post-operative chemotherapy, (b) received at least one cycle, (c) had no progressive recurrence or metastasis 2) Patient was received chemotherapy including 75 mg/m2 or more of epirubicin, and 60 mg/m2 or more of doxorubicin in initial cycle 3) Patient was treated with either (a) Non-aprepitant therapy - patient was treated with a 5HT3-receptor antagonist and dexamethasone from the first cycle through the last cycle between January 2008 and December 2012, or (b) Aprepitant therapy (b-I) patient was treated with a 5HT3-receptor antagonist, dexamethasone, and aprepitant from the first cycle of chemotherapy between December 2009 and December 2012, (b-II) patient was treated with a 5HT3-receptor antagonist, dexamethasone, and aprepitant on the way since the second cycle of chemotherapy between December 2009 and December 2012 4) Day and dosage of anticancer drugs and antiemetic drugs can be identified in clinical record 5) Patient had never received any cancer chemotherapy other than the above EC/FEC or AC regimen with/without prior taxane treatment

Exclusion criteria

Exclusion criteria: -

Design outcomes

Primary

MeasureTime frame
Percent of patients with 85% or more in relative dose intensity of epirubicin or doxorubicin

Countries

Japan

Contacts

Public ContactTakahiro Nakayama

Osaka Medical Center for Cancer and Cardiovascular Disease Department of breast and endocrine surgery

06-6972-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026