The effects of oral nutritional supplement (ONS) during chemoradiotherapy in patients with pancreatic and/or esophageal cancer

The effects of oral nutritional supplement (ONS) during chemoradiotherapy in patients with pancreatic and/or esophageal cancer - The effects of ONS during chemoradiotherapy in patients with pancreatic and/or esophageal cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006274

Enrollment

Registered

2011-10-01

Start date

2010-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with pancreatic and/or esophageal cancer, who are scheduled to receive chemoradiotherapy

Interventions

For the interventional group, an amount of 500ml/day of oral nutritional supplement(Ensure)is administered for patients who receive chemoradiotherapy(CRT)This nutrition intervention is performed from

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with pancreatic and/or esophageal cancer, who are scheduled to receive chemoradiotherapy 2.Histologically confirmed pancreatic and/or esophageal cancer 3.Patients of age =>20 4.Life expectancy more than 2 months 5.Performance Status: 0-2 (ECOG) 6.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Patients on TPN [total parenteral nutrition] 2.Patients with milk protein allergy 3.Patients with Dysphagia 4.Patients who are judged inappropriate for the entry into the study by the investigater

Design outcomes

Primary

Measure	Time frame
To evaluate the effects of Oral Nutritional Supplement (before chemoradiotherapy, 3 weeks after the beginning of chemoradiotherapy and 1 week after chemoradiotherapy) using the Prognostic Nutrition Index (PNI)	—

Secondary

Measure	Time frame
Serum albumin level Lymphocyte count Arm circumference(AC) Triceps subcutaneous fat(TSF) Body weight and body composition Amount of food intake QOL(EORTC QLQ-C30)	—

Countries

Japan

Contacts

Public ContactTatsuya Ioka

Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Medical Oncology

ioka-ta@mc.pref.osaka.jp06-6972-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026