Usefulness of the Kupffer phase study of contrast-enhanced ultrasound using Sonazoid for detection of hepatocellular carcinoma.

Usefulness of the Kupffer phase study of contrast-enhanced ultrasound using Sonazoid for detection of hepatocellular carcinoma. - Kupffer phase study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006226

Enrollment

300

Registered

2011-09-01

Start date

2011-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis patients due to alcoholic or virus with the platelet count is under 150,000 /ul

Interventions

Screening by Kupffer phase of contrast-enhanced ultrasound using Sonazoid. Screening by conventional B-mode US.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Age over 20 2) Hepatitis patients with the platelet count is under 150,000 /ul 3) No history of HCC 4) Inpatient or outpatient 5) Patients who signed a written informed consent form

Exclusion criteria

Exclusion criteria: 1) History of hypersensitivity to egg yolk 2) Pregnant or lactating women and women who may be pregnant 3) Severe liver dysfunction(AST, ALT,or BIL level >10ULN 4) Associated with HCC 5) Paients receiving interferon 6) Age under 20 7) Judged by investigator not to be appropriate for inclusion in this study

Design outcomes

Primary

Measure	Time frame
Detection of Hepatocellular carcinoma	—

Secondary

Measure	Time frame
Size of tumor Numbers of tumor Detection of focal liver lesion	—

Countries

Japan

Contacts

Public ContactIwai Shuji

Osaka Socio-Medical Center Hospital Department of Internal Medicine

osmc1970@eagle.ocn.ne.jp06-6649-0321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026