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Effect of antiepileptic drugs on pharmacokinetics of midazolam during anesthesia in patients with intellectual disability

Effect of antiepileptic drugs on pharmacokinetics of midazolam during anesthesia in patients with intellectual disability - Effect of antiepileptic drugs on pharmacokinetics of midazolam

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000006225
Enrollment
40
Registered
2011-08-24
Start date
2009-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental patients with epilepsy

Interventions

None listed

Sponsors

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Participants of the present study were dental patients with intellectual disability in Okayama University Hospital.

Exclusion criteria

Exclusion criteria: Patients taking other antiepileptic drugs without carbamazepine or phenytoin.

Design outcomes

Primary

MeasureTime frame
We measured the serum concentration of midazolam after injection, and compared them between the groups. More over, we compared clinical effects.

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026