type2 diabetes
Conditions
Interventions
Group A: control observation period (water,meal tolerance test)--washout--in stage 1 (BASEN,meal tolerance test)--washout--in stage 2(GLUBES,meal tolerance test)--washout--in stage 3 (GLUFAST,meal Tol
Sponsors
Advanced Clinical Research Organization
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients treated only by a diabetes diets and exercise regimen or Patients who can have a washout period of glucositase inhibitor or glinide for more than 4weeks. 2) Patients who have been type2 diabetes blow 10 years. 3) Patients who is possible to ingest the test meal (a set of chicken cream, crackers and soft pudding). 4) Adult patients (>=20years) (at the time taking an agreement) 5) Outpatients 6) Patients who can voluntary agree to this study after being taken an explanation for significance and objectives of this study.
Exclusion criteria
Exclusion criteria: 1) Patients having been treated by sulfonylureas within 3 months. 2) Patients treated by hyperlipidemia of fibrates. 3) Patients with a BMI of 40 or more. 4) Patients falling under the [contraindication] in attached files of the experimental drugs. 5) Patients falling under the [Special caution needed] in attached files of the experimental drugs and whom have high disability, and whom principal investigator concludes to be unsuitable for the test. 6) Patients whom principal investigator concludes to be unsuitable for the test, in other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy endpoints: Measure the summary statistics of the measurement value and the changing value of the parameter (glucose, insulin, triglycerides, RLP-C, free fatty acids) after a meal tolerance test. Measure the summary statistics of Emax, tmax and AUEC0-180. Safety endpoints: The incidence of adverse events and side effect. For laboratory evidence, summary statistics are calculated. | — |
Countries
Japan
Contacts
Public ContactErika Yamagishi
NPO Advanced Clinical Research Organization NPO Advanced Clinical Research Organization
Outcome results
None listed