Oral choline tolerance test for nonalcoholic steatohepatitis as non-invasive diagnostic method

Oral choline tolerance test for nonalcoholic steatohepatitis as non-invasive diagnostic method - Oral choline tolerance test for nonalcoholic steatohepatitis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006192

Enrollment

Registered

2011-08-18

Start date

2011-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with nonalcoholic fatty liver disease

Interventions

The subjects received the oral administration ofcholine (260 mg) under fasting conditions over 12 hours, following that 1-h to 4-h samples (plasma) are obtained.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: a.Obtaining informed consent b.Diagnosis as nonalcoholic fatty liver disease

Exclusion criteria

Exclusion criteria: a.HBs Ag(+) or HCV Ab(+) b.AMA(+) c.Alcohol consumption more than 20 g ethanol/day. d.The patient who has possibility of other liver diseases e.Woman who are pregnant or with a possibility of pregnancy f.Renal dysfunction g.Heart failure h.Drug allergy i.Inadequate ot entry to this study

Design outcomes

Primary

Measure	Time frame
Comparison of the plasma free choline levels of fasting and 1-h to 4-h samples with the diagnosis obtained by the liver biopsy	—

Countries

Japan

Contacts

Public ContactKento Imajo

Yokohama City University Graduate School of Medicine Division of Gastroenterology

045-787-2640

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026