A randomized controlled trial for the prevention of Japanese cedar pollinosis by sublingual immune therapy for the subjects with positive sensibilization having not symptoms

A randomized controlled trial for the prevention of Japanese cedar pollinosis by sublingual immune therapy for the subjects with positive sensibilization having not symptoms - Prevention of Japanese cedar pollinosis by sublingual immune therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006180

Enrollment

300

Registered

2011-08-17

Start date

2011-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese cedar pollinosis

Interventions

From December 2011 to Apirl 2012, patients of control 1 receive active treatment everyday. The induction/build-up phase is 2 weeks,with an increasing daliy number of the extract drops at two consentra

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)There is not medical history of cedar pollinosis 2)Positive specific IgE to cry j1/2 antigen(CAP-RAST>=class2)

Exclusion criteria

Exclusion criteria: 1)Pregnant women and those at risk of pregnancy 2)lactating woman 3)Complication of the other nasal-paranasal disease

Design outcomes

Primary

Measure	Time frame
Affirmation of symotoms by cedar pollen antigen provocation test after cedar pollen scattering	—

Secondary

Measure	Time frame
1.Change of parameters in blood. 2.Safty.	—

Countries

Japan

Contacts

Public ContactSyuji Yonekura

Chiba University Graduate School Department of Otorhinolaryngology

syonkura@faculty.hiba-u.jp043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026