Diagnosis of glaucoma with MRI and PET using [11C](R)-PK11195

Diagnosis of glaucoma with MRI and PET using [11C](R)-PK11195 - Glaucoma diagnosis with PK11195-PETand MRI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006156

Enrollment

Registered

2011-08-12

Start date

2011-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

intravenous injection of [11C](R)-PK11195 (3MBq/kg body weight, 180MBq for 60 kg body weight)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with primary open angle glaucoma and healthy adults

Exclusion criteria

Exclusion criteria: High myopic eye ( more than -8.00 diopters), eyes with other diseases, eyes with highly advanced loss of visual fields, eyes with visual field loss due to other diseases, claustrophobic

Design outcomes

Primary

Measure	Time frame
The presence or absence, if present the extent of intensiy , of accumulation at lateral geniculate body on PET	—

Secondary

Measure	Time frame
Perimetric changes, optic nerve cupping, changes of the optic nerve on MRI	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026