Evaluation of Aboral Pouch Reconstruction After Total Gastrectomy in Patients with Gastric Cancer : A Prospective Randomized Controlled Trial

Evaluation of Aboral Pouch Reconstruction After Total Gastrectomy in Patients with Gastric Cancer : A Prospective Randomized Controlled Trial - CCOG1101

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006155

Enrollment

Registered

2011-08-16

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

A: Roux-en-Y reconstruction B: Aboral pouch reconstruction

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1st inclusion criteria (before surgery) 1) Histologically proven primary gastric adenocarcinoma 2) Candidate for R0 surgery by total gastrectomy for patients with gastric cancer 3) Length of esophageal invasion less than or equal to 3cm with no need for thoracotomy for resection 4) Borrmann type 4 and large (8cm or more in diameter) type 3 excluded 5) Not cancer of the remnant stomach 6) No history of upper abdominal surgery and no history of intestinal resection 7) No prior treatment of chemotherapy or radiation therapy against any other malignancies 8) Age 20 to 80 years old 9) PS (ECOG) of 0 or 1 10) Adequate organ functions for gastrectomy 11) Written informed consent from the patient 2nd inclusion criteria (during surgery) 1) cT1 - cT4a 2) cN0-2 H0 P0 M0 3) R0 resection possible, or R1 resection due only to CY1 4) No need for thoracotomy

Exclusion criteria

Exclusion criteria: 1) Synchronous or metachronous (within 5 years) malignancies other than carcinoma in situ 2) Body mass index more than 28 3) Uncontrollable hypertension or uncontrollable diabetes mellitus 4) Continuous systemic steroid therapy 5) Otherwise considered inadequate for inclusion in this trial by the physician

Design outcomes

Primary

Measure	Time frame
Assessment of Quality of Life after Total Gastrectomy	—

Secondary

Measure	Time frame
Body weight Nutritional status Operation time Blood loss during the operation Surgical complications	—

Countries

Japan

Contacts

Public ContactYuichi Ito

Aichi Cancer Center Hospital Department of Gastroenterological Surgery

yuichi@aichi-cc.jp052-762-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026