Donor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: HLA-matched or three antigen mismatched-related donor Basically recommend related donor To give written informed consent To based on the standard of indication for donor (Japan Marrow Donor Program 2007)
Exclusion criteria
Exclusion criteria: Patients have hereditary or secondary coagulopathy, pulmonary embolism,and deep vein thronbosis. Patients have risk factors of pulmonary embolism. Patients suggested as ineligible by their attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of perfusion method for bone marrow cell collection | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time, No. of puncture sites, Total bone marrow cell volume, Total cell counts, Ht, CD3(+), CD34(+), CFU-C, CFU-F | — |
Countries
Japan