Phase II study of TS-1 + CPT-11 for squamous cell lung cancer previously treated with platinum

Phase II study of TS-1 + CPT-11 for squamous cell lung cancer previously treated with platinum - TS-1+CPT-11 for platinum-resistant squamous cell lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006065

Enrollment

Registered

2011-08-01

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer (squamous cell carcinoma)

Interventions

TS-1+CPT-11

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Pathologically proven squamous cell lung cancer 2. Previously treated with 1 or 2 regimen including at least one platinum regimen 3. With measurable lesion 4. With ECOG PS 0-1 5. With adequate organ function 6. With written informed consent

Exclusion criteria

Exclusion criteria: 1. With obvious interstitial pneumonitis 2. With active other malignancies 3. With massive effusion required tube drainage 4. With severe comorbidities 5. With symptomatic brain metastasis 6. With other conditions that is considered inappropriate for the study by an attending physician

Design outcomes

Primary

Measure	Time frame
Response rate	—

Countries

Japan

Contacts

Public ContactAkira Inoue

North Japan Lung Cancer Group Office

akinoue@idac.tohoku.ac.jp+81-22-717-8539

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026