Effect of green tea consumption on pharmacokinetics and pharmacodynamics of nadolol in healthy volunteers

Effect of green tea consumption on pharmacokinetics and pharmacodynamics of nadolol in healthy volunteers - Green tea - nadolol interaction study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006064

Enrollment

Registered

2011-08-01

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Subjects take 700 mL of catechin-rich green tea every day for 14 days, and receive 30 mg of nadolol orally with green tea on day 15. Subjects take 700 mL of water every day for 14 days, and receive 30

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults

Exclusion criteria

Exclusion criteria: Smoker

Design outcomes

Primary

Measure	Time frame
Plasma concentration of nadolol Urinary excretion of nadolol Blood pressure and heart rate	—

Countries

Japan

Contacts

Public ContactShingen Misaka

Fukushima Medical University Department of Pharmacology

misaka@fmu.ac.jp024-547-1156

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026