Schizophrenia, Schizoaffective disorder
Conditions
Interventions
Two-day (two times in the morning and in the evening per day), 20Hz active rTMS procedure and one-month observation period
Two-day (two times in the morning and in the evening per day), sham procedure
Sponsors
Department of Psychiatry, Graduate School of Medicine, Chiba University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A) Don't reach score 0 of auditory hallucination in AHRS, regardless of pharmacotherapy of antipsychotics with sufficient dose and duration. B)"Sufficient dose" refers to more than 600mg/day chlorpromazine-equivalent dose and "sufficient duration" refers to more than 4 weeks.
Exclusion criteria
Exclusion criteria: 1) Traumatic brain injury with loss of consciousness 2) With cripping device or electrode of deep brain stimulation 3) With embedding cochlea stimulating device 4) With cardiac pacing device 5) Epilepsy 6) Abuse or dependence of alcohol or any illegal drugs 7) Mental retardation or personality disorder 8) Cerebrovascular disease 9) Severe neurological disease 10) Under treatment of severe infection disease or malignancy 11) Pregnant woman 12) Left-handed 13) judged inappropriate to participate into the study by medical doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Auditory Hallucination Rating Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and Negative Syndrome Scale, Brief Psychiatric Rating Scale | — |
Countries
Japan
Contacts
Public ContactNobuhisa Kanahara
Graduate School of Medicine, Chiba University Department of Psychiatry
Outcome results
None listed