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An observational study examining endothelium-dependent vasodilatation before and after high-dose rosuvastatin therapy

An observational study examining endothelium-dependent vasodilatation before and after high-dose rosuvastatin therapy - Examination of endothelium-dependent vasodilatation before and after high-dose rosuvastatin therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000006029
Enrollment
50
Registered
2011-07-23
Start date
2011-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia

Interventions

None listed

Sponsors

Osaka City University Graduate School of Medicine Department of Internal medicine and Cardiology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with hyperlipidemia who provide written informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with familiar hyperlipidemia 2) Patients with rosuvastatin hypersensitivity 3) Patients with abnormal values of laboratory tests 4) Patients with kidney transplantation or dialysis 5) Patients with administration of cyclosporine 6) Pregnant women, or nursing women 7) Patients with history of hypothyroidism, hereditary myopathy, drug-induced muscle disorder or family history of hereditary myopathy 8) Patients with drug abuse, or alcoholism 9) Patients with malignant disease

Design outcomes

Primary

MeasureTime frame
Endothelium-dependent vasodilatation

Countries

Japan

Contacts

Public ContactMinoru Yoshiyama

Osaka City University Graduate School of Medicine Department of Internal medicine and Cardiology

yoshiyama@med.osaka-cu.ac.jp06-6645-3801

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026