Induction chemoradiotherapy followed by surgery without mediastinal lymphnode disection in stage IIIA(bulkyN2)/IIIB non-small cell lung cancer

Induction chemoradiotherapy followed by surgery without mediastinal lymphnode disection in stage IIIA(bulkyN2)/IIIB non-small cell lung cancer - Induction chemoradiotherapy followed by surgery without mediastinal lymphnode disection in stage IIIA(bulkyN2)/IIIB non-small cell lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000006022

Enrollment

Registered

2011-07-31

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

Induction chemoradiotherapy followed by surgery without mediastinal lymphnode disection in stage IIIA(bulkyN2) /IIIB non-small cell lung cancer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Histologically or cytologically confirmed non-small cell lung cancer. 2)Stage IIIA(bulkyN2)/IIIB lung cancer. 3)No prior treatment 4)Resectable primary tumor. 5)More than 16 years old-less than 75 years old. 6)PS0-1 7)At least one or more measurable lesion by RECIST. 8)Adequate organ function. 9)Written Informed Consent.

Exclusion criteria

Exclusion criteria: 1)Active co-morbidities. 2)Interstitial lung disease. 3)Active infection. 4)Severe heart disease. 5)Contralateral hilar lymphnode metastasis 6)Neurological disorder. 7)Active double cancer. 8)Psychotic disorder. 9)Histology of grave allergic reaction. 10)Pregnancy, breast feeding and supected pregnancy. 11)Patients whose participation in the trial is judged to be inappropriate.

Design outcomes

Primary

Measure	Time frame
Feasibility	—

Secondary

Measure	Time frame
OS, PFS, efficacy of induction chemoradiotherapy, severe adverse effects of surgery.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026