non-small cell lung cancer
Conditions
Interventions
Induction chemoradiotherapy followed by surgery
Sponsors
Iseikai Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or cytologically confirmed non-small cell lung cancer. 2)Stage IV lung cancer. 3)EGFR mutation status negative. 4)No prior chemotherapy. 5)N o prior radiotherapy. 6)Resectable primary tumor. 7)More than 16 years old-less than 75 years old. 8)PS0-1 9)At least one or more measurable lesion by RECIST. 10)Adequate organ function. 11)Written Informed Consent.
Exclusion criteria
Exclusion criteria: 1)Active co-morbidities. 2)Symptomatic brain metastasis. 3)Interstitial lung disease. 4)Active infection. 5)Severe heart disease. 6)Massive pleural, cardiac effusion, or ascites needed with treatment. 7)Neurological disorder. 8)Active double cancer. 9)Psychotic disorder. 10)Histology of grave allergic reaction. 11)Pregnancy, breast feeding and supected pregnancy. 12)Patients whose participation in the trial is judged to be inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility | — |
Secondary
| Measure | Time frame |
|---|---|
| OS, PFS, efficacy of chemoradiotherapy and severe adverse effecs of surgery | — |
Countries
Japan
Contacts
Public ContactYoshiyasu Nagato
Iseikai Hospital Respiratory Disease Center
Outcome results
None listed