the study of "the effect of the psychotropic (hypnotic) drug on sleep quality, cognitive function and daily activity in patients with chronic hypercapnic respiratory failure who have received nocturnal noninvasive positive pressure ventilation for a long time."

the study of "the effect of the psychotropic (hypnotic) drug on sleep quality, cognitive function and daily activity in patients with chronic hypercapnic respiratory failure who have received nocturnal noninvasive positive pressure ventilation for a long time." - the effect of the hypnotics on sleep in hypercapnic patients receiving nocturnal NPPV

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005989

Enrollment

Registered

2011-08-01

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with chronic hypercapnic respiratory failure receiving a long-term noninvasive positive pressure ventilation (NPPV)

Interventions

Intervention 1:Zolpidem(5mg), one night =&gt

(one week) =&gt

placebo, one night Intervention 2:placebo, one night =&gt

Zolpidem(5mg), one night

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) chronic hypercapnic respiratory failure (2) receiving a long-term NPPV (more than 2 months) (3) Clinically stable

Exclusion criteria

Exclusion criteria: (1) Clinically unstable (2) Unable to discontinue hypnotics

Design outcomes

Primary

Measure	Time frame
Sleep quality, nocturnal transcutneous PCO2	—

Secondary

Measure	Time frame
subjective sleep quality, cognitive function and daily activity	—

Countries

Japan

Contacts

Public ContactTomomasa Tsuboi

Natonal Hospital Orgnization Minami-Kyoto Hospital Department of Respiratory Medicine

tsuboit@skyoto.hosp.go.jp0774-52-0065

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

the study of &quot;the effect of the psychotropic (hypnotic) drug on sleep quality, cognitive function and daily activity in patients with chronic hypercapnic respiratory failure who have received nocturnal noninvasive positive pressure ventilation for a long time.&quot;