Randomized, double-blind, placebo-controlled trial of efficacy of mometasone furoate nasal spray in the initial treatment of Japanese cedar pollinosis

Randomized, double-blind, placebo-controlled trial of efficacy of mometasone furoate nasal spray in the initial treatment of Japanese cedar pollinosis - Efficacy of mometasone in the initial treatment of Japanese cedar pollinosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005986

Enrollment

Registered

2011-07-15

Start date

2009-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese cedar pollinosis

Interventions

In February 1st, 2010, patients begin to receive mometasone (200 ug per day). This treatment was continued until the end of April for 12 weeks. In February 1st, 2010, patients begin to receive placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (a) at least two year history of JCCP; (b) sensitization to Japanese cedar pollen assessed by skin prick test; (c) ability to fill in the diary cards accurately

Exclusion criteria

Exclusion criteria: (a) concomitant sinonasal disease affecting the outcomes of this trial (e.g. nasal polyps, rhinosinusitis, nasal septum deviation); (b) concomitant treatment-requiring allergic rhinitis caused by allergens other than Japanese cedar/cypress pollen; (c) rhinitis medicamentosa and non-infectious, non-allergic rhinitis; (d) cedar pollen-specific immunotherapy; (e) sinonasal surgery including laser vaporization of inferior turbinates within 1 year; (f) medication with anti-allergic drugs including antihistamines, chromons, glucocorticoids and decongentants within 2 weeks; (g) hypersensitivity to MFNS; (h) systemic infection including mycosis; (i) pregnancy and breastfeeding

Design outcomes

Primary

Measure	Time frame
Nasal symptom score	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026