Effect of dexmedetomidine on the local anesthetic action and the circulatory system

Effect of dexmedetomidine on the local anesthetic action and the circulatory system - Effect of dexmedetomidine on the local anesthetic action and the circulatory system

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005961

Enrollment

Registered

2011-07-11

Start date

2011-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy body

Interventions

We inject with 0.7% Lidocaine solution(EC50)1ml under the mouth mucosa.And we measure the local perception using Pain Vision(R) and blood pressure, heart rate,arrhythmia,and oxygen saturation as measu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy body. Student and ataff of okayama university hospital with agreement.

Exclusion criteria

Exclusion criteria: 1. hypersensitivity 2. hypertension,diabetes, hyperthyroidism,arteriosclerosis 3. dyshepatia,dysnephria 4. cardiovascular disease 5. serious arrhythmia 6. taking antipsychotic drugs or alfa-blocker 7. taking catecholamine drugs or adrenergic drugs 8. sensitive to sympathomimetic drugs 9. psychoneurosis or cocaine poisoning 10. dental phobia 11. a pregnant woman or the lactation period 12. a researcher think unsuitable 13. hypertension or arrhythmia at history taking 14. taking medicine

Design outcomes

Primary

Measure	Time frame
Measuring the local perception using Pain Vision(R) and blood pressure, heart rate,arrhythmia,and oxygen saturation as measured using pulse oximetry.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026