The efficacy of lafutidine on heartburn in patients with mild gastroesophageal reflux disease (GERD)

The efficacy of lafutidine on heartburn in patients with mild gastroesophageal reflux disease (GERD) - The efficacy of lafutidine on heartburn in patients with mild gastroesophageal reflux disease (GERD)

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005943

Enrollment

Registered

2011-07-07

Start date

2011-07-01

Completion date

Unknown

Last updated

2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild gastroesophageal reflux disease

Interventions

Lafutidine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: 1) Patients with hypersensitivity for Lafutidine 2) Patients with serious liver abnormality 3) Patients who took gastric acid inhibitors such as proton pump inhibitor and H2 blocker within 1 week 4) Patients who taking medicine which interfere with the study 5) Patients with depression symptoms 6) Patients considered inappropriate by the study investigator

Design outcomes

Primary

Measure	Time frame
Evaluation of GERD symptoms using Frequency Scale for the Symptoms of GERD (FSSG)	—

Secondary

Measure	Time frame
Record of symptoms Frequency of heartburn during day and night Evaluation of QOL using Face Scale	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026