Clinical multi-center study of OTC periodontal ointment-containing applicator with brush (MC2) for reducing risk of relapse of chronic periodontitis during supportive periodontal therapy

Clinical multi-center study of OTC periodontal ointment-containing applicator with brush (MC2) for reducing risk of relapse of chronic periodontitis during supportive periodontal therapy - Clinical multi-center study of OTC periodontal ointment-containing applicator with brush (MC2)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005844

Enrollment

Registered

2011-06-24

Start date

2011-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis

Interventions

test After it brushes with a prescribed fluoridated dentifrice and a toothbrush, the proper quantity (rice grain outline 0.03g teeth) of the test preparations spread two times of the day (morning and

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Person who has ended initial preparation (Surgical treatment is included) of chronic periodontitis, stabilizes the condition, and passes one year or more from SPT beginning in the university hospitals of the clinical trial. (2) 20-year-old or more person (3) Person who remains 15 present numbers or more of teeth (4) Person whom explanation is received by using explanation book, and patient himself agrees to by document

Exclusion criteria

Exclusion criteria: (1) Person while being getting pregnant or suckling (2) Person who has allergy symptom for either of three active compounds (cetylpyridinium chloride, dipotassium glycyrrhizate and allantoin) (3) Person who has systemic disease (diabetic and autoimmune disease) that influences periodontal tissue (4) Person who takes anticoagulant or has tendency to hemorrhages (5) Person of while undergoing cancer therapy (6) Person who received organ transplant in the past (7) Person who took medicines such as antibiotics and antiphlogistic within three months in the past (8) Person who did local drug delivery system of antibiotic in mouth within three months in the past (9) Person who judged that charge dentist is not suitable

Design outcomes

Primary

Measure	Time frame
Probing pocket depth(PPD) Bleeding score(BOP score) Gingival index(GI)	—

Secondary

Measure	Time frame
Number of bacteria in subgingival plaque Clinical attachment level(CAL) Plaque control record(PCR) Probing attachment level in horizontal and vertical direction(PAL-H, PAL-V)	—

Countries

Japan

Contacts

Public ContactShogo Takashiba

Okayama University Department of Pathophysiology - Periodontal Science, Graduate School of Medicine, Dentistry and Pha

stakashi@cc.okayama-u.ac.jp086-235-6675

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026