Clinical trial for efficacy of proactive sequential therapy using topical active Vitamin D and corticosteroids on psoriatic vulgaris

Clinical trial for efficacy of proactive sequential therapy using topical active Vitamin D and corticosteroids on psoriatic vulgaris - Efficacy of proactive sequential therapy on psoriatic vulgaris

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005814

Enrollment

Registered

2011-07-01

Start date

2011-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriatic vulgaris

Interventions

Exam.1. Topically apply Antebate ointment once a day for 2 weeks. Exam. 2. Patients who reach PASI 50 (more than 50% improvement of PASI score) in exam. 1 are divided into two groups by random allocat

Group A receive Antebate ointment reactive to aggravation of skin symptoms and group B receive Antebate ointment twice weekly. Both groups receive daily Dovonex ointment in addition to the treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion: Moderately to severely affected patients with psoriasis vulgaris who are 20 years old or above.

Exclusion criteria

Exclusion criteria: 1. Patients who receive oral cyclosporine, methotrexate and corticosteroids, ultraviolet therapy or any biologics. 2. Patients who are allergic to either Antebate- or Dovonex ointment. 3. Patients who are pregnant

Design outcomes

Primary

Measure	Time frame
Psoriasis area and severity index (PASI) score	—

Countries

Japan

Contacts

Public ContactTakeshi NAKAHARA

Kyushu University Hospital Department of Dermatology

nakahara@dermatol.med.kyushu-u.ac.jp092-642-5585

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026