Phase I/II trial of carboplatin, TS-1, and concurrent radiation therapy in elderly patients with locally advanced non-small cell lung cancer

Phase I/II trial of carboplatin, TS-1, and concurrent radiation therapy in elderly patients with locally advanced non-small cell lung cancer - Phase I/II trial of CBDCA+TS-1+RT in elderly patients with locally advanced NSCLC

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005794

Enrollment

Registered

2011-06-20

Start date

2011-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

carboplatin, TS-1, and concurrent thoracic radiation therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Pathologically diagnosed as non-small cell lung cancer 2) Unresectable locally advanced 3) Clinical stage III (UICC 7th edition) 4) Indication of radical thoracic radiation therapy 5) No prior chemotherapy or radiation therapy 6) Performance status 0-1 7) Age of 71 years or older 8) Adequate organ function 9) Life expectancy of at least 3 months 10) Written informed consent

Exclusion criteria

Exclusion criteria: 1) Active concomitant malignancy 2) Infection, ileus, vomiting 3) Uncontrolled ulcer, diabetes mellitus 4) Interstitial pneumonia 5) Drug allergy

Design outcomes

Primary

Measure	Time frame
progression-free survival rate at one year	—

Countries

Japan

Contacts

Public ContactSeiji Niho

National Cancer Center Hospital East Department of Thoracic Oncology

siniho@east.ncc.go.jp04-7133-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026