Effects of continuous sciatic nerve block added to continuous femoral nerve block for postoperative analgesia after total knee arthroplasty

Effects of continuous sciatic nerve block added to continuous femoral nerve block for postoperative analgesia after total knee arthroplasty - Effects of continuous sciatic nerve block added to continuous femoral nerve block for postoperative analgesia after total knee arthroplasty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005789

Enrollment

Registered

2011-07-01

Start date

2011-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing unilateral total knee arthroplasty under general anesthesia

Interventions

Femoral and sciatic nerve blocks are performed just before surgery and perineural catheters are inserted for both peripheral nerves. After surgery, continuous sciatic nerve block (5 ml/h of 0.2% ropiv

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients undergoing unilateral total knee arthroplasty

Exclusion criteria

Exclusion criteria: ASA physical status above 3 Fixed valgus and flexion deformities Rivision knee replacement Impaired cognitive function Neuromuscular diseases Vascular diseases on lower extremities Diabetes mellitus with insulin therapy Morbid obesity (body mass index > 35) Impaired renal function (serum creatinine > 1.5) Contraindication for peripheral nerve blocks (coagulation abnormalities, infection at the puncture site, allegy to local anesthetics) Gastric ulcer Allergy to NSAIDs Pregnancy or breast feeding

Design outcomes

Primary

Measure	Time frame
Total morphine consumption within 48 hours after surgery	—

Secondary

Measure	Time frame
Visual analogue scale scores, incidence of adverse effects of morphine, the maximum angle of the continuous passive motion of the operated knee on the postoperative day 7 and hospital length of stay	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026