Randomized study of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) versus transesophageal bronchoscopic ultrasound-guided fine needle aspiration (TEBUS-FNA) using an EBUS bronchoscope

Randomized study of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) versus transesophageal bronchoscopic ultrasound-guided fine needle aspiration (TEBUS-FNA) using an EBUS bronchoscope - Randomized study of EBUS-TBNA versus TEBUS-FNA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005757

Enrollment

110

Registered

2011-06-11

Start date

2011-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hilar/mediastinal lesions

Interventions

EBUS-TBNA TEBUS-FNA

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with lesions 10 mm or greater in short-axis diameter on CT adjoining both esophagus and trachea/bronchus, who need to undergo diagnostic bronchoscopy for the decision of management 2. 20 years old or more 3. Informed consent

Exclusion criteria

Exclusion criteria: 1. Patients with lesions proven pathologically 2. Patients for mediastinal lymph node staging 3. Patients needing to undergo other bronchoscopic procedures (e.g. TBB, BAL, brushing) 4. Serious concomitant medical illness 5. Bleeding tendency 6. Pregnant woman 7. Other clinical difficulties in this study

Design outcomes

Primary

Measure	Time frame
1. Patient comfort with EBUS-TBNA vs. TEBUS-FNA assessed by visual analog scale	—

Secondary

Measure	Time frame
1. Anxiety, satisfaction, coughing, vomiting, pain, dyspnea, willing to repeat procedure 2. Time of procedure 3. Diagnostic yield 4. Frequency of adverse effects 5. Oxygen desaturation 6. Doses of a sedative and an anesthetic	—

Countries

Japan

Contacts

Public ContactMasahide Oki

Nagoya Medical Center Department of Respiratory Medicine

masahideo@aol.com052-951-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026