The effect of H1-antihistamine on equilibrium: a double-blind, placebo-controlled study in healthy volunteers

The effect of H1-antihistamine on equilibrium: a double-blind, placebo-controlled study in healthy volunteers - The effect of H1-antihistamine on pustural control

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005751

Enrollment

Registered

2011-06-10

Start date

2010-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic diseases

Interventions

Nine healthy volunteers were recruited and orally administered d-chlorpheniramine 2 mg. Nine healthy volunteers were recruited and orally administered d-chlorpheniramine 4 mg. Nine healthy volunteers

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We enrolled 27 healthy, young adult volunteers.

Exclusion criteria

Exclusion criteria: All subjects had unremarkable medical histories and no history of vertigo, hearing loss, or visual problems except for standard refractive errors.

Design outcomes

Primary

Measure	Time frame
This study was conducted in order to evaluate the effects of d-chlorpheniramine on postural stability using posturography with and without foam rubber. Postural sway was measured before and after medication.	—

Countries

Japan

Contacts

Public ContactYasuhiro Chihara

The University of Tokyo Department of Otolaryngology

y-chihara@umin.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026