Randomized study of Lanthanum Carbonate in hemodialysis patients compared with Calcium Carbonate on coronary artery calcification

Randomized study of Lanthanum Carbonate in hemodialysis patients compared with Calcium Carbonate on coronary artery calcification - Randomized study of Lanthanum Carbonate in hemodialysis patients compared with Calcium Carbonate on coronary artery calcification

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005670

Enrollment

Registered

2011-05-30

Start date

2011-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis patients with hyperphosphatemia

Interventions

Lanthanum carbonate treatment for 2 year Calcium carbonate treatment for 2 year

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Newly initiated hemodialysis patients -Age >20 years old -Ability to understand and willingness to sign a written Informed Consent

Exclusion criteria

Exclusion criteria: -Patients who will meet the contraindication according to package insert -Severe GI disorders -History of obstructed bowels -Severe liver dysfunction -Pregnant or possibly pregnant women and women on lactation -Ineligible patients according to the investigator's judgment

Design outcomes

Primary

Measure	Time frame
-Coronary artery calcification -Major Adverse Cardiovascular Events	—

Secondary

Measure	Time frame
-Coronary stenosis -Aortic valve/Mitral valve calcification left ventricular ejection fraction -Descending aorta calcification -Pi and Ca level achievement rate as defined by local guideline -Albmin, intact-PTH, ALP, hs-CRP -Bone metabolism marker -Bone density -nPCR -Adverse drug reaction	—

Countries

Japan

Contacts

Public ContactMASAHITO TAMURA

UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH KIDNEY CENTER

mtamura@med.uoeh-u.ac.jp093-603-1611

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026