Phase I/II study of adjuvant therapy after liver transplantation in the recipients with advanced hepoatocellular carcinoma

Phase I/II study of adjuvant therapy after liver transplantation in the recipients with advanced hepoatocellular carcinoma - Phase I/II study of adjuvant therapy after LTx in the recipients with advanced HCC

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005667

Enrollment

Registered

2011-06-01

Start date

2006-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplant recipients with advanced hepatocellular carcinoma beyond Milan criteria

Interventions

S-1, Interferon

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Liver transplant recipints with HCC over Milan criteria

Exclusion criteria

Exclusion criteria: renal dysfunction, ABO incompatible transplant, HIV positive, and others

Design outcomes

Primary

Measure	Time frame
safety, recurrence rate and site of HCC	—

Secondary

Measure	Time frame
graft survival, patient survival, incidence of acute cellular rejection and chronic rejection	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026