The evaluation of the effect of losartan on central blood pressure via sympathetic tone and endothelial function

The evaluation of the effect of losartan on central blood pressure via sympathetic tone and endothelial function - LOCSE

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005653

Enrollment

Registered

2011-05-28

Start date

2006-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

anti-hypertensive medication

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: hypertensive subjects having the indcation for anti-hypertensive medication(according to the guideline of JSH2009)

Exclusion criteria

Exclusion criteria: severe renal dysfunction

Design outcomes

Primary

Measure	Time frame
Redunction of central blood pressure	—

Secondary

Measure	Time frame
pulse wave velocity endothlial function heart rate variability BNP uric acid left ventricular mass index	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026